Data taken from: US National Library of Medicine, National Institutes of Health, the FDA, and UMassAmherst
Phthalates
“Several epidemiological studies suggest fetal and childhood exposure to some phthalates may perturb normal development, with several studies consistently reporting increased risk of allergic diseases with DEHP and BBzP exposure.”
http://www.ncbi.nlm.nih.gov/pubmed/23429708
“Emerging evidence from observational studies suggests that prenatal exposure to phthalates affects neurodevelopment in children.” http://www.ncbi.nlm.nih.gov/pubmed/26101203
“Increasing evidence suggests that endocrine-disrupting chemicals (EDCs) contribute to male reproductive diseases and disorders.”http://www.ncbi.nlm.nih.gov/pubmed/25742517
“We show for the first time that exposure to diethyl phthalate, the parent compound of MEP, may be associated with increased risk of BC [breast cancer], whereas exposure to the parent phthalates of MBzP and MCPP might be negatively associated. These findings require confirmation.” http://www.ncbi.nlm.nih.gov/pubmed/20368132
“Reliable data are lacking on whether phthalates, the plasticizing and solvent chemicals found in such products as cosmetics, shampoo, flooring and medical tubing, affect human breast cancer risk. Now epidemiologist Katherine Reeves at the University of Massachusetts Amherst is leading the largest study to date investigating a possible relationship with a three-year, $1.5 million grant from the National Institute of Environmental Health Sciences.”
https://www.umass.edu/newsoffice/article/umass-amherst-epidemiologist-leads-large (UMass Amherst Epidemiologist Leads Large New Study of Phthalate Exposure and Breast Cancer Risk)
Parabens
“parabens can be viewed as potential contributors to breast cancer progression.”
http://www.ncbi.nlm.nih.gov/pubmed/25128701
“With the continued use of parabens in the majority of bodycare cosmetics, there is a need to carry out detailed evaluation of the potential for parabens, together with other oestrogenic and genotoxic co-formulants of bodycare cosmetics, to increase female breast cancer incidence, to interfere with male reproductive functions and to influence development of malignant melanoma which has also recently been shown to be influenced by oestrogenic stimulation.”
http://www.ncbi.nlm.nih.gov/pubmed/18484575
“As an enabling characteristic parabens can cause DNA damage at high concentrations in the short term but more work is needed to investigate long-term, low-dose mixtures. The ability of parabens to enable multiple cancer hallmarks in human breast epithelial cells provides grounds for regulatory review of the implications of the presence of parabens in human breast tissue.”
http://www.ncbi.nlm.nih.gov/pubmed/25047802
“Although increasing data suggest that exposure to EDCs [endocrine disrupting chemicals, including phthalate and parabens] is linked to transgenerational inheritance of reproductive, metabolic, or neurological phenotypes, more studies are needed to validate these observations and to elucidate further whether these developmental changes are directly associated with the relevant epigenetic alterations.
http://www.ncbi.nlm.nih.gov/pubmed/26026600
Triclosan
“FDA does not have evidence that triclosan added to antibacterial soaps and body washes provides extra health benefits over soap and water.”
http://www.fda.gov/ForConsumers/ConsumerUpdates/ucm205999.htm
“these results suggest that TCS and OP may promote breast cancer progression”
http://www.ncbi.nlm.nih.gov/pubmed/24684733
“. . . these results indicated that TCS and BP-1 may enhance the progression of PCa by regulating cell cycle and metastasis-related genes via AR signaling pathway.”
http://www.ncbi.nlm.nih.gov/pubmed/25682003
“Current laboratory studies in various species provide strong evidence for its disrupting effects on the endocrine system, especially reproductive hormones. “
http://www.ncbi.nlm.nih.gov/pubmed/26184583
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